There are two main medications used to treat hair loss: finasteride and minoxidil. Finasteride is FDA-approved to treat hair loss, while minoxidil is often used "off-label," which means healthcare providers prescribe it even though it was originally made for other health issues. Some men prefer oral minoxidil because it has a lower risk of sexual side effects than finasteride. Since these two medications work in different ways, your healthcare provider will look at your medical history and your personal preferences to help you decide which treatment is the best and safest fit for your lifestyle.